Hoppa yfir valmynd

Hugtakasafn ţýđingamiđstöđvar utanríkisráđuneytisins

Ritstjóri: Sigrún Ţorgeirsdóttir
Leitarorđ Leitartungumál
Nánari leit  |  Fletting sviđa

Hugtakasafn : Eitt hugtak
ÍSLENSKA
3T3-NRU-ljóseiturhrifaprófun
ENSKA
3T3 NRU phototoxicity test
DANSKA
3T3 NRU-fototoksicitetstest
SĆNSKA
3T3 NRU-fototoksicitetstest
FRANSKA
essai de phototoxicité 3T3
ŢÝSKA
3T3-NRU-Fototoxizitätstest
Sviđ
íđefni
Dćmi
vćntanlegt
Skilgreining
[en] this Test Guideline describes a method to evaluate photo-cytotoxicity by the relative reduction in viability of cells exposed to the chemical in the presence versus absence of light (OECD library, úr Test No. 432: In Vitro 3T3 NRU Phototoxicity Test)

test used to identify the phototoxic effect of a test substance induced by the combination of test substance and light and is based on the comparison of the cytotoxic effect of a test substance when tested after the exposure and in the absence of exposure to a non-cytotoxic dose of UVA/vis light. Cytotoxicity is expressed as a concentration-dependent reduction of the uptake of the vital dye - Neutral Red. (IATE);

the 3T3 Neutral Red Uptake Phototoxicity Test 83T3 NRU PT) is designed to detect the phototoxicity induced by the combined action af a chemical and light by usind an in vitro cytotoxicity assay with the Balb/c 3T3 mouse fibrroblast cell line. The test identifies compounds that act in vivo phototoxic after systemic application, as well as compounds, including UV filter chmicals, that act as photoirritants after topical application and distribution to the skin (ECVAM)

Rit
[is] Reglugerđ framkvćmdastjórnarinnar (EB) nr. 440/2008 frá 30. maí 2008 ţar sem mćlt er fyrir um prófunarađferđir samkvćmt reglugerđ Evrópuţingsins og ráđsins (EB) nr. 1907/2006 um skráningu, mat, leyfisveitingu og takmarkanir ađ ţví er varđar efni (efnareglurnar (REACH))
[en] Commission Regulation (EC) No 440/2008 of 30 May 2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)

Skjal nr.
32008R0440
Athugasemd
[is] Sjá Íđorđasafn lćkna í Orđabanka Árnastofnunar (e. phototoxicity)
[en] The ''3T3'' designation refers to the abbreviation of "3-day transfer, inoculum 3 x 105 cells. This cell line was originally established from the primary mouse embryonic fibroblast cells that were cultured by the designated protocol, so-called ''3T3 protocol'' (Wikipedia)

Orđflokkur
no.
Kyn
kvk.
ENSKA annar ritháttur
3T3 NRU PT
3T3 Neutral Red Uptake Phototoxicity Assay

Var efniđ hjálplegt?Nei
Takk fyrir

Ábendingin verđur notuđ til ađ bćta gćđi ţjónustu og upplýsinga á vef Stjórnarráđsins. Hikađu ekki viđ ađ hafa samband ef ţig vantar ađstođ.

Af hverju ekki?

Hafa samband

Ábending / fyrirspurn


Ţessi síđa notar vafrakökur Lesa meira